CAMRIS is seeking a Structural Biology Scientist to support the Walter Reed Army Istitute of Research (WRAIR) Wound Infection Department.
WRAIR aims to conduct biomedical research that is responsive to Department of Defense and US Army requirements and delivers life-saving products including knowledge, technology and medical material that sustain the combat effectiveness of the Warfighter.
WRAIR’s vision is to be the premier DoD biomedical research organization, constantly relevant, integrating basic research and advanced technology that protects, projects, and sustains the Warfighter today, invents global medical solutions for the future, and keeps the Warfighter on point for the Nation. WRAIR host three Centers of Excellence for Military Psychiatry and Neuroscience Research, Military Infectious Disease Research, and Enabling Capabilities Research; each center ranging from blast induced neurotrauma to malaria vaccine development.
This position is for a proposal.
- Perform research on structure based drug design for microbial pathogens of military relevance and animal testing (a minimum of 5 studies or as required).
- Develop and recommend drug candidates for specific targets on ESKAPEE pathogens (Enterococcus species, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter cloacae, and Escherichia coli) for antimicrobial development and approval by the team lead and department chief (a minimum of one annually or as required).
- Draft grant proposals on structure based drug design for submission and approval by the department chief and research steering committees (a minimum of five proposals annually or as required) and report to the COR annually. Proposal due dates will be set by funding agencies. Status updates of this task shall be included in the monthly report.
- Conduct research on projects associated with antimicrobial development (a minimum of five studies or as required) such as protein expression and purification (five or more), MIC (minimum inhibitory concentration experiments >five annually) studies, animal modeling, virtual modeling of drugs bound to target proteins, etc.
- Deliver novel small molecules and peptides, express, purify and crystallize proteins for structure-based drug design, and mass spectrometry of all products.
- MD or Ph.D. in Microbiology, chemistry, physical chemistry, Physiology, Molecular Biology, Biochemistry or other related scientific field.
- Senior Scientist II shall have experience in at least one of the following areas: protein chemistry, purification methods, animal models, and structural biology, x-ray crystallography, biophysical techniques