Vertex is seeking a talented individual to join the Engineering and Materials Science group in Boston, MA. The successful candidate will be a highly productive, results-oriented individual, able to multi-task and generate and implement original ideas that contribute to the successful development and scale-up of drug substance candidates. Strong communication, organization, and planning skills and a high level of technical aptitude and creativity are required for success in this position.
The Chemical Engineering Scientist supports Vertex’s drug development programs by applying fundamental engineering science to the development of pipeline candidates and to the creation of robust drug substance and drug product manufacturing processes. This role will design and execute chemistry and engineering experiments under limited supervision.
Key Duties and Responsibilities:
- Have demonstrated laboratory experience in the development of one or more of the following unit operations: liquid phase organic synthesis, crystallization, reaction engineering, or other aspects relevant to fine chemical or drug substance processing. Possess a sound fundamental and applied understanding of the chemical engineering principals behind these unit operations
- Support fine chemical / drug substance process development via laboratory development and pilot plant scale-up. Conceive, execute and interpret synthetic organic and engineering-related laboratory experiments with a high degree of reliability and independence
- Possess a sound scientific understanding of chemistry and chemical engineering fundamentals and an understanding of applied kinetics, thermodynamics, and transport fundamentals, as well as familiarity with modern laboratory instrumentation
- Assist in the timely development of novel and creative technical solutions to overcome scale-up and manufacturing obstacles
- Possess excellent communication and interpersonal skills and have the ability to interact and collaborate within a large interdisciplinary team comprised of chemical engineers; organic, physical, and analytical chemists; materials and solid-state scientists, and formulation development scientists
Knowledge and Skills:
- Experience with statistical design of experiments and familiarity with common physical property and process modeling tools (Aspen, Dynochem, Matlab, gPROMS, etc.).
- Demonstrated ability to develop solutions to open-ended problems with creativity and innovation
- Effective collaboration skills that translate well to successful work within multidisciplinary teams
- Strong verbal and written communication skills
- Participates in department/group discussions
- Searches for opportunities to broaden impact within department
- Strong, independent experimentalist
- Exhibits strong chemical engineering principles
- Proven productivity and experimental creativity
- Effective communication skills with no guidance
- Independently prepares presentations/reports and presents experimental data, conclusions and recommendations
Education and Experience:
- Bachelor’s degree in Chemical Engineering or a related discipline
- Typically requires a PhD and 0-3 years, a Master’s and 3+ years, a Bachelor’s and 6+ years, or the equivalent combination of education and experience related to Chemical Engineering